Media Reports & Press Releases
Breast Cancer Risk Increases With Repeated CT Imaging
(posted January 2013) -- Researchers reviewing the records of approximately 250,000 women enrolled in an integrated healthcare delivery system found that increased CT utilization between 2000 and 2010 could result in an increase in the risk of breast cancer for certain women, including younger patients and those who received repeat exams. This appeared in the Clinical Cancer Letter, Vol. 35, No. 12, December 2012. (A paid subscription is required to view the content.)
Gierach GL, et al. Relationship between mammographic density and breast cancer death in the Breast Cancer Surveillance Consortium. Journal of National Cancer Institute. This paper was discussed in two news releases:
(posted January 2013) -- The risk of dying from breast cancer was not related to high mammographic breast density in breast cancer patients.
- Tracy Onega's paper was recognized as Editor's Choice in the Clinical Practice category for 2012.
- (posted September 2013) -- Recognition of this award was published in the January 2013 issue of JACR.
- Six BCSC papers were selected for publication in Radiology Select: Breast Cancer Screening's fourth collection.
- (posted September 2013) -- Each collection has approximately 30 articles selected as the best research and review articles published in Radiology in the last 5-7 years. They also held a video podcast at RSNA (November, 2012) with some of the authors on these papers. See the list of the six BCSC papers:
- Rosenberg RD, Yankaskas BC, Abraham LA, Sickles EA, Lehman CD, Geller BM, Carney PA, Kerlikowske K, Buist DS, Weaver DL, Barlow WE, Ballard-Barbash R. Performance benchmarks for screening mammography. Radiology. 2006 Oct;241(1):55-66. [View Abstract]
- Buist DS, Anderson ML, Haneuse SJ, Sickles EA, Smith RA, Carney PA, Taplin SH, Rosenberg RD, Geller BM, Onega TL, Monsees BS, Bassett LW, Yankaskas BC, Elmore JG, Kerlikowske K, Miglioretti DL. Influence of Annual Interpretive Volume on Screening Mammography Performance in the United States. Radiology. 2011 Apr;259(1):72-84. Epub 2011 Feb 22. [View Abstract]
- Carney PA, Sickles EA, Monsees BS, Bassett LW, Brenner RJ, Feig SA, Smith RA, Rosenberg RD, Bogart TA, Browning S, Barry JW, Kelly MM, Tran KA, Miglioretti DL. Identifying minimally acceptable interpretive performance criteria for screening mammography. Radiology. 2010 May;255(2):354-61. This article was the #3 most-read article in Radiology from May-July 2010. [View Abstract]
- Yankaskas BC, May RC, Matuszewski J, Bowling JM, Jarman MP, Schroeder BF. Effect of Observing Change from Comparison Mammograms on Performance of Screening Mammography in a Large Community-based Population. Radiology. 2011 Dec;261(3):762-70. doi: 10.1148/radiol.11110653. Epub 2011 Oct 26. [View Abstract]
- Schell MJ, Yankaskas BC, Ballard-Barbash R, Qaqish BF, Barlow WE, Rosenberg RD, Smith-Bindman R. Evidence-based target recall rates for screening mammography. Radiology. 2007 Jun;243(3):681-9. [View Abstract]
- Elmore JG, Jackson S, Abraham L, Miglioretti DL, Carney PA, Geller B, Yankaskas BC, Kerlikowske K, Onega T, Rosenberg RD, Sickles EA, Buist DSM. Variability in interpretive performance of screening mammography and radiologist characteristics associated with accuracy. Radiology. 2009 Dec;253(3):641-51. Epub 2009 Oct 28. [View Abstract]
- A UCSF Press release came out in conjunction with electronic publication in JNCI of Dejana Braithwaite's manuscript, "Screening outcomes in older U.S. women undergoing multiple mammograms in community practice: does interval, age or comorbidity score affect tumor characteristics or false positive rates?"
- The Breast Cancer Surveillance Consortium: A Valuable Research Resource
- (posted January 2013) This appeared in the Applied Research Program, Spotlight on Applied Research, Issue 3.
- Risk factors may inform breast cancer screening; mammograms might benefit women in their 40s with family history or dense breasts
- (posted January 2013) -- Choosing when to start regular breast cancer screening is a complicated decision for individual women and their providers.
- Yearly mammograms? Expect a 'false positive' each decade; Annals of Internal Medicine publishes Group Health-led national study
- (posted January 2013) -- Cumulative probability of false-positive recall or biopsy recommendation after 10 years of screening mammography.
- Stopping hormones might help breast cancer to regress
- (posted January 2013) -- Screening mammography use among current, former, and never hormone therapy users may not explain recent declines in breast cancer incidence.
- Screening mammograms catch second breast cancers early
- (posted January 2013) -- More women are surviving longer after having early-stage breast cancer, but they are at risk of developing breast cancer again.
- Scientists Uncover New Key to the Puzzle of Hormone Therapy and Breast Cancer
- (posted November 9, 2009) --
The use of postmenopausal hormone therapy has decreased over time in the United
States, which BCSC researchers suggest may play a key role in the declining rate
of atypical ductal hyperplasia, a known risk factor for breast cancer.
- After Menopause, Weight Affects Breast Cancer Rates More than Mammography Use
- (posted December 5, 2008) --
Results published by the BCSC show that post menopausal women who are overweight
have an increased risk of breast cancer that is not explained by the frequency
or accuracy of their previous mammograms.
- Breast Density in Mammography and Cancer Risk
- (posted November 10, 2008) --
BCSC investigators discuss recent findings, hypotheses, and clinical considerations surrounding the role of breast density in breast cancer risk.
- Researchers Validate New Model for Breast Cancer Risk Assessment in Multiple Ethnic Groups
- (posted March 5, 2008) --
Researchers at the University of California, San Francisco have developed a way to quickly
estimate a woman's risk for invasive breast cancer. The new model, based on a measure of
breast density that is already reported with the majority of mammograms today, is the
first to be validated across multiple ethnic groups living in the United States.
- Radiologist Characteristics Associated with Interpretive Performance of Diagnostic Mammography
- (posted December 12, 2007) --
Radiologists' interpretation of diagnostic mammograms varies widely and could not be
explained by differences in patient populations, according to a study published online
December 11 in the Journal of the National Cancer Institute. This variation could affect
clinical decisions in large numbers of women.
- Declines in Invasive Breast Cancer and Use of Postmenopausal Hormone Therapy in a Screening Mammography Population
- (posted August 22, 2007) --
Between 2002 and 2003, the incidence of breast cancer declined nearly 7 percent in the
United States and remained low through 2004. This sharp decrease was reported in December
2006, and since then researchers have been trying to explain the good news. BCSC
investigators examined screening rates and hormone use in more than 600,000 women from
1997 through 2003. Researchers found the decline in mammography rates is unlikely to
explain the recent decline in U.S. breast cancers while a drop in hormone use is a more
- Computer-aided Detection Reduces the Accuracy of Mammograms
- (posted April 5, 2007) --
Computer-aided detection (CAD) that uses software designed to improve how radiologists
interpret mammograms may instead make readings less accurate, according to new research.
Use of CAD did not clearly improve the detection of breast cancer. The research was
conducted by investigators at the University of California Davis Health System,
Sacramento, Calif., and colleagues in the Breast Cancer Surveillance Consortium, which is
sponsored by the National Cancer Institute (NCI), part of the National Institutes of
- Improving Mammography Quality, Expanding Screening Research
- (posted March 22, 2007) --
A new study using BCSC data published in the March 7
Journal of the National Cancer Institute discusses an important piece of information on
the use of breast density in calculating risk: that two or more measurements of density
over time may be better at predicting risk than a single measurement.
- BCSC AIM Project Highlighted in Society of Breast Imaging Newsletter (PDF)
- (posted January 19, 2007) --
The National Cancer Institute's (NCI's) Breast Cancer Surveillance Consortium (BCSC) was
recently awarded $2.5 million from the Breast Cancer Stamp Fund and the American Cancer
Society to help support new research on how to improve mammographic interpretation. The
title of the project is "Assessing and Improving Mammography (AIM)". The funding provided
by the American Cancer Society is provided through a generous donation from the
Longaberger® Company's Horizon of Hope Campaign®. This is a novel collaboration among
public and private agencies that builds on the BCSC's history of collaborative research.
- Breast Density Helps Predict Breast Cancer Risk
- (posted September 6, 2006) --
Two new models for assessing patients' risk of developing breast cancer focus on breast
density as an important predictor, two studies report in the September 6 issue of the
Journal of the National Cancer Institute.
(Also see the National Cancer Institute Fact Sheet
"Estimating Breast Cancer Risk:
Questions and Answers".)
- Mammography Screenings for Breast Cancer Show Racial and Ethnic Disparities
- (posted April 17, 2006) --
Researchers at the University of California San Francisco site
have found that inadequate use of screening mammography may be an important reason that
African-American women are more likely to be diagnosed with advanced stage breast cancer
than members of other ethnic groups.
- Medical Malpractice Concerns Lead to More Breast Biopsies
- (posted June 28, 2005) --
Some women may be undergoing unnecessary diagnostic imaging and
breast biopsies because radiologists are worried about medical malpractice suits,
according to a study in the July issue of Radiology.
- Older Doctors Specializing in High Volume Screening Mammography Deliver More Accurate Results
- (posted March 1, 2005) --
Physicians who specialize in screening mammography and who have at
least 25 years of experience are more accurate at interpreting the images and subject
fewer women to the anxiety of false positives for cancer, when compared to physicians with
less experience or those who don't have the same focus, according to a new study.
- Breast Implants Interfere with Mammograms (PDF)
- (posted January 27, 2004) --
Breast implants decrease the ability of mammography to detect breast cancer, according to
a large national study led by researchers from Breast Cancer Surveillance Consortium. This
study is published in the January 28 issue of the Journal of the American Medical